Probiotics, gut microbiome, and cardiovascular diseases: An update

Abstract

"Cardiovascular diseases (CVD) are one of the most challenging diseases and many factors have been demonstrated to affect their pathogenesis. One of the major factors that affect CVDs, especially atherosclerosis, is the gut microbiota (GM). Genetics play a key role in linking CVDs with GM, in addition to some environmental factors which can be either beneficial or harmful. The interplay between GM and CVDs is complex due to the numerous mechanisms through which microbial components and their metabolites can influence CVDs. Within this interplay, the immune system plays a major role, mainly based on the immunomodulatory effects of microbial dysbiosis and its resulting metabolites. The resulting modulation of chronic inflammatory processes was found to reduce the severity of CVDs and to maintain cardiovascular health. To better understand the specific roles of GM-related metabolites in this interplay, this review presents an updated perspective on gut metabolites related effects on the cardiovascular system, highlighting the possible benefits of probiotics in therapeutic strategies."

For the whole article:

Probiotics, gut microbiome, and cardiovascular diseases: An update 

Comments

Post a Comment

Popular posts from this blog

Research finds dramatic increase in cranial traumas as the first cities were being built, suggesting a rise in violence

Image
 " The development of the earliest cities in Mesopotamia and the Middle East led to a substantial increase in violence between inhabitants. Laws, centralized administration, trade and culture then caused the ratio of violent deaths to fall back again in the Early and Middle Bronze Age (3,300 to 1,500 BCE). This is the conclusion of an international team of researchers from the Universities of Tübingen, Barcelona and Warsaw. Their  results  were published in  Nature Human Behaviour ." https://phys.org/news/2023-10-cranial-traumas-cities-built-violence.html
Read more

Hook, Line, and Sinker: Mt. Ebal Curse Tablet Debunked?

Image
 " Initially hailed by its discoverers as “the most ancient Hebrew inscription ever found,” the  controversial Mt. Ebal curse tablet  may be no more than a common fishing weight. At least that is the suggestion of archaeologist Amihai Mazar, who published his interpretation of the artifact in the  Israel Exploration Journal , alongside two other articles skeptical of the discoverers’ claims." For more details: 1.  Hook, Line, and Sinker: Mt. Ebal Curse Tablet Debunked? 2. An Early Israelite Curse Inscription from Mt. Ebal? 3. “You are Cursed by the God YHW:” an early Hebrew inscription from Mt. Ebal And a related book: The Iron Age I Structure on Mt. Ebal: Excavation and Interpretation
Read more