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Showing posts from April, 2024

Scientists made a six-legged mouse embryo — here’s why

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 " Researchers have long known that, in most four-limbed animals, both the external genitalia (penis or clitoris) and hind limbs develop from the same primordial structures. When Mallo’s team looked further into the six-legged mouse phenomenon, they found that Tgfbr1 directs these structures to become either genitalia or limbs by altering the way that DNA folds in the structure’s cells. Deactivating the protein changed the activity of other genes, resulting in extra limbs and no true external genitalia." For more details: Scientists made a six-legged mouse embryo — here’s why And a related book: https://amzn.to/3xnu3ex

Nasal rinsing: why flushing the nasal passages with tap water to tackle hay fever could be fatal

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 " Nasal rinsing or irrigation is an increasingly popular technique to manage hay fever and other irritants in the nose. It involves pouring or squirting a solution into the nose to help wash out microbes, mucus and other debris such as dust or allergens. There are specialised containers called neti pots that are used to pour water into one nostril, allowing it to run out of the other by tilting your head to the side. Water bottles and other specialised sprays pre-filled with saline solution can also be used. But the practice is not without its risks, not least because if not done with sterile water it can introduce germs into the body. A small number of people, especially those with weakened immune systems, have even died from diseases caught through nasal rinsing. So how can allergy sufferers reap the benefits of nasal rinsing while avoiding the pitfalls?" For more details: Nasal rinsing: why flushing the nasal passages with tap water to tackle hay fever could be fatal And

Therapeutic potential of lipid-lowering probiotics on the atherosclerosis development

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  Abstract "Hypercholesterolemia is a critical risk factor for atherosclerosis, mostly attributed to lifestyle behavior such as diet. Recent advances have emphasized the critical effects of gastrointestinal bacteria in the pathology of hypercholesterolemia and atherosclerosis, suggesting that the gastrointestinal microbiome can therefore provide efficient therapeutic targets for preventing and treating atherosclerosis. Thus, interventions, such as probiotic therapy, aimed at altering the bacterial composition introduce a promising therapeutic procedure. In the current review, we will provide an overview of anti-atherogenic probiotics contributing to lipid-lowering, inhibiting atherosclerotic inflammation, and suppressing bacterial atherogenic metabolites." For more details: Therapeutic potential of lipid-lowering probiotics on the atherosclerosis development And a related book: https://amzn.to/4cGV8cM

Making long-term memories requires DNA damage, researchers discover

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 " Just as you can't make an omelet without breaking eggs, scientists at Albert Einstein College of Medicine have found that you can't make long-term memories without DNA damage and brain inflammation. Their surprising findings were  published  in the journal  Nature  in a paper titled "Formation of memory assemblies through the DNA sensing TLR9 pathway."" For more details: Making long-term memories requires DNA damage, researchers discover And a related book: https://amzn.to/43JLXUD